Mark
I posted way up there in the thread (2nd post) that I was having similar issues to the OP
In fact, on that same site, I've just wiped the entire site, installed WP3.5.1 fresh, added WordFence 3.6.9 as the only plugin, using the default twentytwelve theme ... and WordFence still will not save the Options page nor start a scan.
The only post/comment on the site are the defaults ones when you first install WP. Six months now I've been waiting for you to comment on my problem, and you haven't yet.
As I said above, this is on a VPS, and the other domains on that VPS all run WordFence perfectly. I love WordFence, but getting frustrated my one "problem" is being ignored - I've lost 6 months of site live time waiting for an answer.
I'm stumped on this - any clues you can point at?
Gaz